Okwe is a popular game played by the Igbo people of south eastern Nigeria. This game is a member of the big Mancala family game. This work presents an artificial intelligence (AI) designed to play Okwe efficiently. This work also tries to show the difference in efficiency and performance in using different search algorithms to design the AI. The search algorithms used in this paper are: Random/Brute force, heuristic, minimax and alpha-beta algorithms. The result of this work is a program capable of winning human opponents.